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Products > GPCR > Sigma Receptor > AVex-73 hydrochloride (Synonyms: AE-37 hydrochloride)
Product name : AVex-73 hydrochloride (Synonyms: AE-37 hydrochloride)
Item : C2445
Price : 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com
CAS : 195615-84-0
Molecular Weight : 317.85
Formula : C₁₉H₂₄ClNO
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order.
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Details:
Description of:AVex-73 hydrochloride(CAS:195615-84-0)
AVex-73 hydrochloride is a Sigma-1 Receptor agonist with an IC50 of 860 nM.
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data. 

REFERENCES

[1]. Villard V, et al. Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative. J Psychopharmacol. 2011 Aug;25(8):1101-17.
[2]. Valentine Lahmy, et al. Blockade of Tau Hyperphosphorylation and Aβ1-42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic andσ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer's Disease. Neuropsychopharmacology. 2013 Aug; 38(9): 1706-1723.


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