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Product name : Vorinostat (SAHA)
Item : cc95
Price : 200mg, $55; 500mg, $95; 1g, $155
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
Vorinostat (SAHA) has been shown to bind to the active site of histone deacetylases and act as a chelator for Zinc ions also found in the active site of histone deacetylases Vorinostat's inhibition of histone deacetylases results in the accumulation of acetylated histones and acetylated proteins, including transcription factors crucial for the expression of genes needed to induce cell differentiation.[1][2]
 
Reference:
[1] Int. J Cancer 2007, 121, 656-655.
[2] Mol. Cancer 2010, 9, 49.
 
 
Chemical Information
Molecular Weight (WM):
264.3
Formula:
C14H20N2O3
CAS No:
149647-78-9
Purity:
≥ 98%
Synonyms:
Zolinza
 
DMSO ≥ 53 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol ≥ 5 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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