Favorite  |  Set Home
Products > DNA damage > HDAC > Belinostat (PXD 101)
Product name : Belinostat (PXD 101)
Item : cc489
Price : 10mg, $120; 50mg,$355; 100mg, $545; 200mg,$895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
Belinostat (PXD 101) inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM. It targets tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase. [1][2]
 
Reference:
[1] Mol. Cancer Ther. 2003, 2, 721-728.
[2] Clin. Cancer Res. 2008, 14, 804-810.
 
 
Chemical Information
Molecular Weight (WM):
318.35
Formula:
C15H14N2O4S
CAS No:
414864-00-9
Purity:
≥ 98%
Synonyms:
PXD101, PXD-101. PX105684
 
DMSO ≥ 64 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

Related Products :
HDAC inhibitor
HDAC inhibitor
Price: 10mg, $125; 50mg, $495; 100mg, $695; 200mg, $1095
MC 1568
MC 1568
Price: 10mg, $95, 50mg, $375; 100mg, $655; 200mg, $895
Tacedinaline (CI 994, PD 123654)
Tacedinaline (CI 994, PD 123654)
Price: 50mg, $195; 100mg, $395; 200mg, $695, 1g, $1295
EPZ 5676
EPZ 5676
Price: 10mg, $275; 50mg, $695; 100mg, $1295; 200mg, $2295
Resminostat (4SC-201)
Resminostat (4SC-201)
Price: 10mg, $195; 50mg, $675; 100mg, $965; 200mg, $1655
M 344
M 344
Price: 10mg, $175; 50mg, $595; 100mg, $945; 200mg, $1795
MS 275 (SNDX 275)
MS 275 (SNDX 275)
Price: 10mg, $75, 50mg, $275; 100mg, $395; 200mg, $695
Rocilinostat (ACY 1215)
Rocilinostat (ACY 1215)
Price: 10mg, $125; 50mg, $395; 100mg, $695; 200mg, $995