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Products > DNA damage > HDAC > Droxinostat (NS 41080)
Product name : Droxinostat (NS 41080)
Item : cc490
Price : 10mg, $120; 50mg,$355; 100mg, $745; 200mg,$995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8. Droxinostat shows comparable inhibition of HDAC6 and HDAC8 (IC50 = 2.47 and 1.46 μmol/L, respectively). Evasion of death receptor ligand-induced apoptosis represents an important contributor to cancer development and progression. This agent could sensitize malignant cells to death receptor ligands (FAS and TRAIL). [1]
 
Reference:
[1] Mol. Cancer Ther. 2010, 9, 246-256.
 
 
Chemical Information
Molecular Weight (WM):
243.69
Formula:
C11H14ClNO3
CAS No:
99873-43-5
Purity:
≥ 98%
Synonyms:
NS41080, NS-41080
 
DMSO ≥ 49 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol ≥ 49 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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