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Products > DNA damage > HDAC > Trichostatin A (TSA)
Product name : Trichostatin A (TSA)
Item : cc238
Price : 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 58880-19-6
Molecular Weight : 302.37
Formula : C₁₇H₂₂N₂O₃
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
Trichostatin A (TSA) is a potent, reversible inhibitor of histone deacetylase (HDAC). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of the HDAC1 with an IC50 value of 70 nM.1 Trichostatin A selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. [1][2]
 
Reference:
[1] J Med. Chem. 2010, 53, 7202-7218.
[2] Science 1996, 272, 408-411.
   
 
Chemical Information
Molecular Weight (WM):
302.37
Formula:
C17H22N2O3
CAS No:
58880-19-6
Purity:
≥ 98%
Synonyms:
TSA
 
DMSO ≥ 61 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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