Trichostatin A/TSA/58880-19-6/acesobio supply

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Product name : Trichostatin A (TSA)

Item : cc238

Price : 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190

contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.

CAS : 58880-19-6

Molecular Weight : 302.37

Formula : C₁₇H₂₂N₂O₃

Storage : at -20°C

Additional information : We offer significant discount for larger quantity order

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Details:

Trichostatin A (TSA) is a potent, reversible inhibitor of histone deacetylase (HDAC). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G₁ and inhibits the activity of the HDAC1 with an IC₅₀ value of 70 nM.^{1 Trichostatin A selectively inhibits the removal of acetyl groups from the amino-}terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. ^[1][2]

Reference:

[1] J Med. Chem. 2010, 53, 7202-7218.

[2] Science 1996, 272, 408-411.

Chemical Information

Molecular Weight (WM):	302.37
Formula:	C₁₇H₂₂N₂O₃
CAS No:	58880-19-6
Purity:	≥ 98%
Synonyms:	TSA
	DMSO ≥ 61 mg/mL
Solubility: (R.T.: 25℃):	Water < 1 mg/mL
	Ethanol < 1 mg/mL
	2 years -20℃ Powder
Stability:	2 weeks -4℃ in DMSO
	2 months -80℃ in DMSO