Product name : TG100-115
Item : cc492
Price : 200mg, $650;500mg, $1050; 1g $1650; 2g, $2450
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 677297-51-7
Molecular Weight : 346.34
Formula : C₁₈H₁₄N₆O₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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TG100-115, inhibited PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively), whereas both PI3Kα and -β were relatively unaffected (IC50 values>1 μM). As a gauge of general specificity, TG100-115 was also assayed against a 133 protein kinase panel, none of which was inhibited at IC50 values <1 μM.
TG100-115 is applied to anti-inflammatory therapy for respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). TG100-115 could reduce inflammation and mucin accumulation. [1][2] Reference:
[1] J Pharmacol. Exp. Ther. 2009, 328, 758-765.
[2] Biochem. Soc. Trans. 2007, 35, 204-206.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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