Favorite  |  Set Home
Product name : PI 103
Item : cc5
Price : 200mg, $650;500mg, $1050; 1g $1650; 2g, $2450
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 371935-74-9
Molecular Weight : 348.36
Formula : C₁₉H₁₆N₄O₃
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
PI 103 is an inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). It inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.  [1][2]
 
Reference:
[1] Leukemia 2008, 22, 1698-1706.
[2] Cell 2006, 19, 733-747.
 
 
Chemical Information
Molecular Weight (WM):
348.36
Formula:
C19H16N4O3
CAS No:
371935-74-9
Purity:
≥ 98%
Synonyms:
PI-103, PI103
 
DMSO ≥ 24 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

Related Products :
NVP-BAG956
NVP-BAG956
Price: 200mg, $1250;500mg, $2150; 1g $3050; 2g, $4450
GDC 0941
GDC 0941
Price: 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
YM 201636
YM 201636
Price: 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
PIK 294
PIK 294
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
NVP-BKM120 (BKM 120)
NVP-BKM120 (BKM 120)
Price: 2g, $650;5g, $1050; 10g $1650
PIK 75
PIK 75
Price: 200mg, $650;500mg, $1050; 1g $1650; 2g, $2450
AZD 6482
AZD 6482
Price: 200mg, $750;500mg, $1250; 1g $1950; 2g, $3050
LY 294002 (NSC 697286, SF 1101)
LY 294002 (NSC 697286, SF 1101)
Price: 200mg, $450;500mg, $850; 1g $1250; 2g, $1850