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Product name : PI 103
Item : cc5
Price : 10mg, $85; 50mg, $275; 100mg, $595; 200mg, $895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
PI 103 is an inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). It inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.  [1][2]
 
Reference:
[1] Leukemia 2008, 22, 1698-1706.
[2] Cell 2006, 19, 733-747.
 
 
Chemical Information
Molecular Weight (WM):
348.36
Formula:
C19H16N4O3
CAS No:
371935-74-9
Purity:
≥ 98%
Synonyms:
PI-103, PI103
 
DMSO ≥ 24 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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