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Product name : PKI 402
Item : cc193
Price : 200mg, $650;500mg, $1050; 1g $1650; 2g, $2450
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1173204-81-3
Molecular Weight : 570.65
Formula : C₂₉H₃₄N₁₀O₃
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
PKI-402 is a selective, reversible, ATP-competitive, equipotent class I phosphatidylinositol 3-kinases (PI3K) inhibitor with IC50 of 1, 7, 16 and 14 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively. PKI-402 inhibited growth of human tumor cell lines derived from breast, brain (glioma), pancreas, and non-small cell lung cancer tissue and suppressed phosphorylation of PI3K and mTOR effector proteins (e.g., Akt at T308) at concentrations that matched those that inhibited cell growth. [1][2]
 
Reference:
[1] Mol. Caner Ther. 2010, 9, 976-984.
[2] J Med. Chem. 2010, 53, 798-810.
 
 
Chemical Information
Molecular Weight (WM):
570.65
Formula:
C29H34N10O3
CAS No:
1173204-81-3
Purity:
≥ 98%
Synonyms:
PKI 402, PKI402
 
DMSO < 1 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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