Favorite  |  Set Home
Products > PI3K/Akt/mTOR > PI3K > NVP-BGT226 (BGT 226)
Product name : NVP-BGT226 (BGT 226)
Item : cc443
Price : 10mg, $245; 50mg, $725; 100mg, $995; 200mg, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
NVP-BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin. NVP-BGT226 inhibits growth in common myeloma cell lines and primary myeloma cells at nanomolar concentrations in a time-dependent and dose-dependent manner. NVP-BGT226 inhibited phosphorylation of protein kinase B (Akt), P70S6k and 4E-BP-1 in a time-dependent and dose-dependent manner.  [1][2]
 
Reference:
[1] Anticancer Drugs 2012, 23,131-138.
[2] Clin. Cancer Res. 2011, 17, 7116-7126.
 
 
Chemical Information
Molecular Weight (WM):
650.60
Formula:
C28H25F3N6O2 · C4H4O4
CAS No:
1245537-68-1
Purity:
≥ 98%
Synonyms:
BGT-226, BGT 226, BGT226
 
DMSO ≥ 130 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

Related Products :
NVP-BEZ235 (BEZ 235)
NVP-BEZ235 (BEZ 235)
Price: 10mg, $45; 50mg, $85; 100mg, $125; 200mg, $245
ZSTK 474
ZSTK 474
Price: 10mg, $60; 50mg, $245; 100mg, $450; 200mg; $695
NVP-BKM120 (BKM 120)
NVP-BKM120 (BKM 120)
Price: 10mg, $225; 50mg, $875; 100mg, $1275; 200mg, $2175
NVP-BAG956
NVP-BAG956
Price: 10mg, $325; 50mg, $775; 100mg, $1295; 200mg,$1675
CAL 101 (GS 1101)
CAL 101 (GS 1101)
Price: 10mg, $110; 50mg, $335; 100mg, $575; 200mg, $995
A 66
A 66
Price: 10mg, $295; 50mg, $895; 100mg, $1295; 200mg, $1995
PIK 75
PIK 75
Price: 10mg, $55; 50mg, $140; 100mg, $345; 200mg, $545
GDC 0941
GDC 0941
Price: 10mg, $125; 50mg, $325; 100mg, $595; 200mg, $925