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Product name : NVP-BGT226 (BGT 226)
Item : cc443
Price : 200mg, $950;500mg, $1650; 1g $2450; 2g, $3650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1245537-68-1
Molecular Weight : 650.6
Formula : C₃₂H₂₉F₃N₆O₆
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
NVP-BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin. NVP-BGT226 inhibits growth in common myeloma cell lines and primary myeloma cells at nanomolar concentrations in a time-dependent and dose-dependent manner. NVP-BGT226 inhibited phosphorylation of protein kinase B (Akt), P70S6k and 4E-BP-1 in a time-dependent and dose-dependent manner.  [1][2]
 
Reference:
[1] Anticancer Drugs 2012, 23,131-138.
[2] Clin. Cancer Res. 2011, 17, 7116-7126.
 
 
Chemical Information
Molecular Weight (WM):
650.60
Formula:
C28H25F3N6O2 · C4H4O4
CAS No:
1245537-68-1
Purity:
≥ 98%
Synonyms:
BGT-226, BGT 226, BGT226
 
DMSO ≥ 130 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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