Product name : MK 2206
Item : cc295
Price : 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1032350-13-2
Molecular Weight : 480.39
Formula : C₂₅H₂₃Cl₂N₅O
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
|
Details: | |||||||||||||||||||||||||
MK 2206 is an Akt inhibitor, is also an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds to and inhibits the activity of Akt in a non-ATP competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. [1][2]
Reference:
[1] J Med. Chem. 2010, 53, 1413-1437.
[2] J Clin. Endocrinol. Metab. 2011, 96, E577-585.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
|
Related Products : |
|
|
|
|
||||||||
|
|
|
|