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Product name : CHIR 99021 (CT99021)
Item : cc59
Price : 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 252917-06-9
Molecular Weight : 465.34
Formula : C₂₂H₁₈Cl₂N₈
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
CHIR99021 is the most selective inhibitor of glycogen synthase kinase 3β (GSK3β) reported to date. CHIR-99021 (CT99021) has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10μM.[1][2]
 
Reference:
[1] Cancer Res. 2008, 68, 7466-7474.
[2] Expert Opin. Ther. Pat. 2009, 19, 775-799.
 
 
Chemical Information
Molecular Weight (WM):
465.34
Formula:
C22H18Cl2N5
CAS No:
252917-06-9
Purity:
≥ 98%
Synonyms:
CHIR-99021, CT99021, CHIR 99021
 
DMSO ≥ 3 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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