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Product name : Perifosine (KRX-0401)
Item : cc514
Price : 200mg, $449;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 157716-52-4
Molecular Weight : 461.66
Formula : C₂₅H₅₂NO₄P
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
Perifosine (KRX0401) modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine. [1][2]
  
Reference:
[1] Cancer Res. 2002, 62, 1401-1409.
[2] Mol. Cancer Ther. 2003, 2, 1093-1103.
 
 
Chemical Information
Molecular Weight (WM):
461.66
Formula:
C25H52NO4P
CAS No:
157716-52-4
Purity:
≥ 98%
Synonyms:
NSC639966, D-2166, KRX-0401
 
DMSO < 1 mg/mL
Solubility (25℃)
Water ≥ 14 mg/mL
 
Ethanol ≥ 92 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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