Product name : Perifosine (KRX-0401)
Item : cc514
Price : 200mg, $449;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 157716-52-4
Molecular Weight : 461.66
Formula : C₂₅H₅₂NO₄P
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Perifosine (KRX0401) modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine. [1][2]
Reference:
[1] Cancer Res. 2002, 62, 1401-1409.
[2] Mol. Cancer Ther. 2003, 2, 1093-1103.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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