Apoptosis
Serotonin Transporter
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Product name : Celecoxib (Celebrex)
Item : cc518
Price : 5g, $650;10g, $1050; 20g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 169590-42-5
Molecular Weight : 381.37
Formula : C₁₇H₁₄F₃N₃O₂S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Celecoxib (Celebra; Celebrex; SC 58635) is a highly selective COX-2 inhibitor and primarily inhibits this isoform of cyclooxygenase (and thus causes inhibition of prostaglandin production). Celecoxib is more selective for COX-2 (IC50=0.04μM) inhibition over COX-1(IC50=15μM). [2]It binds with its polar sulfonamide side chain to a hydrophilic side pocket region close to the active COX-2 binding site. Celecoxib is a nonsteroidal antiinflammatory drug (NSAID) that is used to treat arthritis, pain, menstrual cramps, and colonic polyps. [1][2]
Reference:
[1] Rheumatology 2007, 46, 135-140.
[2] N. Engl. J Med. 2006, 355, 873-884.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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