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Product name : Celecoxib (Celebrex)
Item : cc518
Price : 100mg, $50, 500mg, $150; 1g, $220
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Celecoxib (Celebra; Celebrex; SC 58635) is a highly selective COX-2 inhibitor and primarily inhibits this isoform of cyclooxygenase (and thus causes inhibition of prostaglandin production). Celecoxib is more selective for COX-2 (IC50=0.04μM) inhibition over COX-1(IC50=15μM). [2]It binds with its polar sulfonamide side chain to a hydrophilic side pocket region close to the active COX-2 binding site. Celecoxib is a nonsteroidal antiinflammatory drug (NSAID) that is used to treat arthritis, pain, menstrual cramps, and colonic polyps. [1][2]
 
Reference:
[1] Rheumatology 2007, 46, 135-140.
[2] N. Engl. J Med. 2006, 355, 873-884.
 
 
Chemical Information
Molecular Weight (WM):
381.37
Formula:
C17H14F3N3O2S
CAS No:
169590-42-5,184007-95-2, 194044-54-7
Purity:
≥ 98%
Synonyms:
Celebrex, Celebra, SC-58635,SC58635
 
DMSO ≥ 76 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 33 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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