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Product name : MK 0974 (Telcagepant)
Item : cc519
Price : 10mg, $425; 50mg, $1195; 100mg, $1995;200mg, $3695
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
MK-0974 (telcagepant) acts as a calcitonin gene-related peptide receptor (CRLR) antagonist and blocks this peptide. It is believed to constrict dilated blood vessels within the brain. The calcitonin gene-related peptide (CGRP) is a strong vasodilator primarily found in nervous tissue. Since vasodilation in the brain is thought to be involved in the development of migraine and CGRP levels are increased during migraine attacks, this peptide may be an important target for potential new antimigraine drugs. [1][2]
 
Reference:
[1] Neurology 1008, 70, 1304-1312.
[2] Lancet 2008, 372, 2115-2123.
 
 
Chemical Information
Molecular Weight (WM):
566.52
Formula:
C26H27F5N6O3
CAS No:
781649-09-0
Purity:
≥ 98%
Synonyms:
MK0974, MK 0974
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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