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Product name : Sunitinib malate (Sutent)
Item : cc354
Price : 50mg, $125; 100mg, $195; 200mg, $275, 1g, $445
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Sunitinib malate (Sutent) is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively). Sunitinib also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Sunitinib exhibits antiangiogenic and antitumor activity in multiple xenograft models. [1][2]
 
Reference:
[1] Nat. Rev. Drug Discov. 2007, 6, 734.
[2] Biochem. Biophys. Res. Commun. 2007, 356, 323-328.
 
 
Chemical Information
Molecular Weight (WM):
532.56
Formula:
C22H27FN4O2·C4H6O5
CAS No:
341031-54-7, 557795-19-4 (free base), 1126641-10-8 ( Maleic acid)
Purity:
≥ 98%
Synonyms:
SU-112468, SU11248, SU 11248
 
DMSO ≥ 15mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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