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Products > Receptor Tyrosine Kinase > IGF-1R > Linstinib (OSI 906)
Product name : Linstinib (OSI 906)
Item : cc217
Price : 10mg, $195; 50mg, $595; 100mg, $895; 200mg, $1355
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
OSI-906 (Linsitinib) is a selective inhibitor of IGF-IR and IR with IC50 of 35 nM and 75 nM, respectively.OSI906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. [1][2]
 
Reference:
[1] Future Med. Chem. 2009, 1, 1153-1171.
[2] Clin. Cancer Res. 2011, 17, 3332-3340.
 
 
Chemical Information
Molecular Weight (WM):
421.49
Formula:
C26H23N5O
CAS No:
867160-71-2
Purity:
≥ 98%
Synonyms:
OSI 906
 
DMSO ≥ 84 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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