Product name : Linstinib (OSI 906)
Item : cc217
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 867160-71-2
Molecular Weight : 421.49
Formula : C₂₆H₂₃N₅O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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OSI-906 (Linsitinib) is a selective inhibitor of IGF-IR and IR with IC50 of 35 nM and 75 nM, respectively.OSI906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. [1][2]
Reference:
[1] Future Med. Chem. 2009, 1, 1153-1171.
[2] Clin. Cancer Res. 2011, 17, 3332-3340.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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