Favorite  |  Set Home
Product name : WZ 4002
Item : cc192
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1213269-23-8
Molecular Weight : 494.97
Formula : C₂₅H₂₇ClN₆O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
WZ4002 is a novel, mutant-selective EGFR kinase inhibitor for EGFR L858R and EGFR L858R /T790M with IC50 of 2 nM and 8 nM, respectively.  WZ-4002 does not inhibit wild-type EGFR; thus, it may have less effect on normal body cells and not cause diarrhea or rash like iressa and tarceva. WZ 4002 is a compound that can inhibit T790M EGFR in the laboratory cells without inhibiting normal EGFR.   [1][2]
 
Reference:
[1] Lab Inves. 2012, 92, 371-383.
[2] Bioorg. Med. Chem. Lett. 2011, 21, 638-643.
 
 
Chemical Information
Molecular Weight (WM):
494.97
Formula:
C25H27ClN6O3
CAS No:
1213269-23-8
Purity:
≥ 98%
Synonyms:
WZ 4002
 
DMSO ≥ 13 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
AST1306(tosylate)
AST1306(tosylate)
Price: 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
BMS 690514
BMS 690514
Price: 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190
Afatinib (BIBW 2992)
Afatinib (BIBW 2992)
Price: 5g, $650;10g, $1050; 20g $1650
Canertinib
Canertinib
Price: 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
Lapatinib (Tykerb)
Lapatinib (Tykerb)
Price: 5g, $650;10g, $1050; 20g $1650
Gefitinib
Gefitinib
Price: 5g, $650;10g, $1050; 20g $1650
CUDC 101
CUDC 101
Price: 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
Varlitinib (ARRY 334543)
Varlitinib (ARRY 334543)
Price: 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395