Apoptosis
Btk
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Product name : AG 490 (Tyrphostin B42)
Item : cc365
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 133550-30-8
Molecular Weight : 294.3
Formula : C₁₇H₁₄N₂O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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AG 490 is a selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively). Inhibitor of JAK2, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways and potently inhibits cytokine-independent cell growth in vitro and tumor cell invasion in vivo. [1][2]
Reference:
[1] J Med. Chem. 1991, 34, 1896-1907.
[2] Nature 1996, 379, 645-648.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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