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Products > Protease > HIV protease > Ritonavir (Synonyms: A 84538; ABT 538; Abbott 84538; NSC 693184; RTV)
Product name : Ritonavir (Synonyms: A 84538; ABT 538; Abbott 84538; NSC 693184; RTV)
Item : cc542
Price : 10mg, $75; 50mg, $275; 100mg, $445; 200mg, $795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 155213-67-5
Molecular Weight : 720.94
Formula : C₃₇H₄₈N₆O₅S₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Ritonavir (Norvir, ABT538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, ritonavir is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). The drug’s molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors. This discovery has drastically reduced the adverse effects and improved the efficacy of PI’s and HAART.  [1][2]
 
Reference:
[1] http://en.wikipedia.org/wiki/Ritonavir
[2] Proc. Natl. Acad.Sci. USA 1995, 92, 2484-2488.
 
 
Chemical Information
Molecular Weight (WM):
720.94
Formula:
C37H48N6O5S2
CAS No:
155213-67-5
Purity:
≥ 98%
Synonyms:
A 84538, NSC 693184, RTV, Abbott 84538
 
DMSO ≥ 144 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 20 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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