Favorite  |  Set Home
Products > Others > MAO > Safinamide (FCE28073)
Product name : Safinamide (FCE28073)
Item : cc549
Price : 10mg, $265; 50mg, $595; 100mg, $895; 200mg, $1295
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]             


Details:
Safinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; ) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals. [1][2]
 
Reference:
[1] J Pharm. Pharmacol. 1994, 46, 814-819.
[2] J Pharmacol. Exp. Ther. 1998, 285, 397-403.
 
 
Chemical Information
Molecular Weight (WM):
398.45
Formula:
C17H19FN2O2·CH4O3S
CAS No:
202825-46-5, 133865-89-1 (free base)
Purity:
≥ 98%
Synonyms:
FCE-28073(R-isomer), PNU-151774E, NW-1015
 
DMSO ≥ 80 mg/mL
Solubility (25℃)
Water ≥ 80 mg/mL
 
Ethanol ≥ 13 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
SL 251188
SL 251188
Price: 10mg, $245; 50mg, $825; 100mg, $1395; 200mg, $2295