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Product name : Darbufelone
Item : cc555
Price : 10mg, $125; 50mg, $595; 100mg, $895; 200mg, $1295
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Darbufelone was discovered as a dual inhibitor of cellular prostaglandin and leukotriene production. Darbufleone potently inhibits PGHS-2 with IC50 of 0.19 μM but is much less potent with PGHS-1 with IC50 of 20μM. Duloxetine (SNK-860) is an aldose reductase inhibitor. Long-term treatment with SNK-860 has a beneficial preventive effect on the development of experimental diabetic neuropathy. [1][2]

Reference:
[1] J Med. Chem. 1994, 37, 322-328.
[2] Biochemistry 2001, 40, 7736-7745.
 
 
Chemical Information
Molecular Weight (WM):
332.46
Formula:
C18H24N2O2S
CAS No:
139226-28-1 
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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