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Product name : CPI 613
Item : cc429
Price : 10mg, $185; 50mg, $695; 100mg, $1275; 200mg, $1895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
CPI-613 is a lipoic acid analog that targets the mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase. In vitro, CPI 613 produces the selective toxicity against several tumor cell lines including H460 human lung cancer cells and Saos-2 human sarcoma cells with EC50 of 120 μM and 120 μM, respectively.CPI613has been shown to inhibit metabolic and regulatory processes required for cell growth in solid tumors. Both enantiomers in the racemic mixture exhibit antineoplastic activity.  [1][2]
 
Reference:
[1] J Mol. Med. 2011, 89, 1137-1148.
[2] Drug Metab. Lett. 2011, 5, 163-182.
 
 
Chemical Information
Molecular Weight (WM):
388.59
Formula:
C22H28O2S2
CAS No:
95809-78-2
Purity:
≥ 98%
Synonyms:
CPI 613
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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