Product name : LX 1606
Item : cc432
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1033805-22-9
Molecular Weight : 574.98
Formula : C₂₇H₂₆ClF₃N₆O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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LX1606 is and orally bioavailable, tryptophan hydroxylase (THP) inhibitor prodrugs. Upon administration, LX-1606 is converted to its active metabolite LP-778902, which binds to and blocks the activity of TPH. This may result in a reduction in peripheral serotonin (5-HT) production and improvement of serotonin-mediated gastrointestinal effects such as severe diarrhea. TPH, the rate-limiting enzyme in serotonin biosynthesis, is overexpressed in carcinoid tumor cells. [1]
Reference:
[1] Biochem. J 2012, 443, 701-709.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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