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Product name : LX 1606
Item : cc432
Price : 10mg, $245; 50mg, $725; 100mg, $1295; 200mg, $1995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
LX1606 is and orally bioavailable, tryptophan hydroxylase (THP) inhibitor prodrugs. Upon administration, LX-1606 is converted to its active metabolite LP-778902, which binds to and blocks the activity of TPH. This may result in a reduction in peripheral serotonin (5-HT) production and improvement of serotonin-mediated gastrointestinal effects such as severe diarrhea. TPH, the rate-limiting enzyme in serotonin biosynthesis, is overexpressed in carcinoid tumor cells.   [1]
 
Reference:
[1] Biochem. J 2012, 443, 701-709.
 
 
Chemical Information
Molecular Weight (WM):
754.2
Formula:
C27H26ClF3N6O3
CAS No:
1033805-22-9, 1137608-69-5
Purity:
≥ 98%
Synonyms:
LX 1606, Telotristat etiprate
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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