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Product name : Nutlin-3a (chiral)
Item : cc452
Price : 200mg, $750;500mg, $1350; 1g $2150; 2g, $3250
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 548472-68-0
Molecular Weight : 581.49
Formula : C₃₀H₃₀Cl₂N₄O₄
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
Nutlin-3 is a MDM-2 antagonist with an IC50 of 90nM. It is the compound most commonly used in anti-cancer studies. Inhibiting the interaction between MDM2 and p53 stabilizes p53 and is thought to selectively induce a growth-inhibiting state called senescence in cancer cell.[1][2][3]
 
Reference:
[1] http://en.wikipedia.org/wiki/Nutlin
[2] Annu. Rev. Pharmacol. Toxicol. 2009, 49, 223-241.
[3] Science 2004, 303, 844-848
                                               
 
Chemical Information
Molecular Weight (WM):
581.5
Formula:
C30H30Cl2N4O4
CAS No:
675576-98-4
Purity:
≥ 98%
Synonyms:
N/A
 
DMSO ≥ 166 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol ≥ 166 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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