Apoptosis
Serotonin Transporter
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Product name : Palonosetron
Item : cc332
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 135729-61-2
Molecular Weight : 296.41
Formula : C₁₉H₂₄N₂O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Palonosetron competitively blocks the action of serotonin at 5-hydroxytryptamine type 3 (5-HT3) receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. The CTZ is located in the area postrema on the dorsal surface of the medulla oblongata at the caudal end of the fourth ventricle and outside the blood-brain barrier (BBB).[1][2]
Reference:
[1] Cancer 2003, 98, 2473-2482.
[2] Expert Opin. Pharmacother. 2003, 4, 2297-2303.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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