Favorite  |  Set Home
Product name : Palonosetron
Item : cc332
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 135729-61-2
Molecular Weight : 296.41
Formula : C₁₉H₂₄N₂O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
Palonosetron competitively blocks the action of serotonin at 5-hydroxytryptamine type 3 (5-HT3) receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. The CTZ is located in the area postrema on the dorsal surface of the medulla oblongata at the caudal end of the fourth ventricle and outside the blood-brain barrier (BBB).[1][2]
 
Reference:
[1] Cancer 2003, 98, 2473-2482.
[2] Expert Opin. Pharmacother. 2003, 4, 2297-2303.
 
 
Chemical Information
Molecular Weight (WM):
332.87
Formula:
C19H25ClN2O
CAS No:
135729-62-3
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

Related Products :
Prucalopride
Prucalopride
Price: 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
naronapride (ATI 7505)
naronapride (ATI 7505)
Price: 200mg, $1750;500mg, $2690; 1g $4190;
Blonanserin
Blonanserin
Price: 500mg, $295; 1g, $495
SB 742457 (GSK 742457)
SB 742457 (GSK 742457)
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
Duloxetine (Cymbalta)
Duloxetine (Cymbalta)
Price: 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
Vilazodone
Vilazodone
Price: 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
Lurasidone (SM 13496)
Lurasidone (SM 13496)
Price: 5g, $650;10g, $1050; 20g $1650
SB 242084
SB 242084
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590