Favorite  |  Set Home
Product name : Palonosetron
Item : cc332
Price : 10mg, $75, 50mg, $245; 100mg, $445; 200mg, $695
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
Palonosetron competitively blocks the action of serotonin at 5-hydroxytryptamine type 3 (5-HT3) receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. The CTZ is located in the area postrema on the dorsal surface of the medulla oblongata at the caudal end of the fourth ventricle and outside the blood-brain barrier (BBB).[1][2]
 
Reference:
[1] Cancer 2003, 98, 2473-2482.
[2] Expert Opin. Pharmacother. 2003, 4, 2297-2303.
 
 
Chemical Information
Molecular Weight (WM):
332.87
Formula:
C19H25ClN2O
CAS No:
135729-62-3
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

Related Products :
naronapride (ATI 7505)
naronapride (ATI 7505)
Price: 10mg, $395; 50mg,$1095; 100mg, $1695; 200mg,$2475
Blonanserin
Blonanserin
Price: 500mg, $295; 1g, $495
LY 310762
LY 310762
Price: 10mg, $75, 50mg, $275; 100mg, $495; 200mg, $795
SB 242084
SB 242084
Price: 10mg, $125; 50mg, $495; 100mg, $895; 200mg, $1495
LY 344864
LY 344864
Price: 10mg, $195; 50mg, $595; 100mg, $895; 200mg, $1455
Tropisetron
Tropisetron
Price: 10mg, $75, 50mg, $275; 100mg, $495; 200mg, $795
SB 742457 (GSK 742457)
SB 742457 (GSK 742457)
Price: 10mg, $265; 50mg, $795; 100mg, $1395; 200mg, $2295
BRL 15572
BRL 15572
Price: 10mg, $75, 50mg, $275; 100mg, $495; 200mg, $695