Favorite  |  Set Home
Products > Transmembrane Transporter > P-gp > LY 335979 (Zosuquidar trihydrochloride, RS 33295-198)
Product name : LY 335979 (Zosuquidar trihydrochloride, RS 33295-198)
Item : cc68
Price : 10mg, $275; 50mg, $795; 100mg, $1395; 200mg, $1895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]             


Details:
LY335979 (Zosuquidar trihydrochloride, RS 33295-198) binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). P-glycoprotein, encoded by the MDR-1 gene, is a member of the ATP-binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product-derived cytotoxic agents.  [1][2]
 
Reference:
[1] Cancer Res. 1996, 56, 4171-4179.
[2] J Pharmacol. Exp. Ther. 2011, 337, 710-717.
 

Chemical Information
Molecular Weight (WM):
636.99
Formula:
C32H32F2N3O2·3HCl
CAS No:
167465-36-3, 167354-41-8 (free base)
Purity:
≥ 98%
Synonyms:
LY-335979, RS-33295-198
 
DMSO ≥ 127 mg/mL
Solubility (25℃)
Water ≥ 23 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
Valspodar (PSC 833)
Valspodar (PSC 833)
Price: 5mg, $275, 10mg, $475, 50mg, $1285, 100mg, $1995
Tariquidar (XR 9576)
Tariquidar (XR 9576)
Price: 10mg, $175; 50mg, $595; 100mg, $945; 200mg, $1795