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Product name : Ciproxifan (FUB 359)
Item : cc128
Price : 10mg, $175; 50mg, $595; 100mg, $945; 200mg, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Ciproxifan (FUB-359), Antagonists of H3-type histamine receptors exhibit cognitive-enhancing properties in various memory paradigms as well as evidence of antipsychotic activity in normal animals.Ciproxifan is an extremely potent histamine H3 inverse agonist/antagonist.Ciproxifan produces wakefulness and attentiveness in animal studies, and produced cognitive enhancing effects without prominent stimulant effects at relatively low levels of receptor occupancy, and pronounced wakefulness at higher doses.It has therefore been proposed as a potential treatment for sleep disorders such as narcolepsy and to improve vigilance in old age, particularly in the treatment of conditions such as Alzheimer's disease.It also potentiated the effects of antipsychotic drugs, and has been suggested as an adjuvant treatment for schizophrenia.[1][2]
 
Reference:
[1] J Pharmacol. Exp. Ther. 1998, 287, 658-666.
[2] Arch. Pharmacol. 1998, 358, 623-627.
 
 
Chemical Information
Molecular Weight (WM):
386.40
Formula:
C16H18N2O2·C4H4O4
CAS No:
184025-19-2, 184025-18-1(free base)
Purity:
≥ 98%
Synonyms:
FUB359
 
DMSO ≥ 54 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 54 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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