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Product name : TAK 285
Item : cc290
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 871026-44-7
Molecular Weight : 547.96
Formula : C₂₆H₂₅ClF₃N₅O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
TAK-285 is a novel dual HER2 and EGFR inhibitor with IC50 of 17 nM and 23 nM, respectively.TAK285 might have the potential in the treatment of brain metastases of HER2 over-expressing metastatic breast cancer.  [1][2]
 
Reference:
[1] J Med. Chem. 2011, 54, 8030-8050.
[2] Br. J Caner 2012, 106, 666-672.
 
 
Chemical Information
Molecular Weight (WM):
547.96
Formula:
C26H25ClF3N5O3
CAS No:
871026-44-7
Purity:
≥ 98%
Synonyms:
TAK 285
 
DMSO ≥ 110 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 54 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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