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Product name : HA 14-1
Item : cc-453
Price : 200mg, $550;500mg, $950; 1g $1650; 2g, $2850
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 65673-63-4
Molecular Weight : 409.23
Formula : C₁₇H₁₇BrN₂O₅
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
HA 14-1, Cell-permeable inhibitor of Bcl-2 protein (IC50 9 μM), acts by binding t the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also binds to the antiapoptotic Bcl-2 protein Bcl-XL and Bcl-w.[1][2]
 
Reference:
[1] Proc. Natl. Acad. Sci. 2000, 97, 7124-7129..
[2] Blood 2002, 99, 3461-3464.
                                           
Chemical Information
Molecular Weight (WM):
409.23
Formula:
C17H17BrN2O5
CAS No:
65673-63-4
Purity:
≥ 98%
Synonyms:
N/A
 
Soluble to 100 mM in DMSO
Solubility: (R.T.: 25℃):
N/A
 
Soluble to 100 mM in ethanol
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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