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Product name : AZD 4547
Item : cc27
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1035270-39-3
Molecular Weight : 463.57
Formula : C₂₆H₃₃N₅O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
AZD-4547 is a novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3 with IC50 of of 0.2 nM, 2.5 nM, and 1.8 nM, respectively. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up-regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation and survival. [1]
 
Reference:
[1] Cancer Res. 2012, 72, 2045-2056.
 
Chemical Information
Molecular Weight (WM):
463.57
Formula:
C26H33N5O3
CAS No:
1035270-39-3
Purity:
≥ 98%
Synonyms:
AZD 4547
 
DMSO ≥ 92 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 12 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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