Apoptosis
MAO
|
Product name : Posaconazole
Item : cc165
Price : 5g, $650;10g, $1050; 20g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 171228-49-2
Molecular Weight : 700.78
Formula : C₃₇H₄₂F₂N₈O₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 |
| Details: | |||||||||||||||||||
Posaconazole (Noxafil) works by disrupting the close packing of acyl chains of phospholipids, impairing the functions of certain membrane-bound enzyme systems such as ATPase and enzymes of the electron transport system, thus inhibiting growth of the fungi. It does this by blocking the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors. Posaconazole is significantly more potent at inhibiting 14-alpha demethylase than itraconazole. [1][2]
Reference:
[1] Clin. Ther. 2007, 29, 1862-1886.
[2] Ann. Pharmacother. 2008, 42, 1429-1438.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
| Related Products : |
|
|
|
|
||||||||
|
|
|
|
Chinese
Deutsch
Espanol
Francais
Italiano
Portugues
Japanese
Korean
Arabic
Russian