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Product name : Posaconazole
Item : cc165
Price : 5g, $650;10g, $1050; 20g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 171228-49-2
Molecular Weight : 700.78
Formula : C₃₇H₄₂F₂N₈O₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Posaconazole (Noxafil) works by disrupting the close packing of acyl chains of phospholipids, impairing the functions of certain membrane-bound enzyme systems such as ATPase and enzymes of the electron transport system, thus inhibiting growth of the fungi. It does this by blocking the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors. Posaconazole is significantly more potent at inhibiting 14-alpha demethylase than itraconazole. [1][2]
 
Reference:
[1] Clin. Ther. 2007, 29, 1862-1886.
[2] Ann. Pharmacother. 2008, 42, 1429-1438.
 
 
Chemical Information
Molecular Weight (WM):
700.78
Formula:
C37H42F2N8O4
CAS No:
171228-49-2
Purity:
≥ 98%
Synonyms:
Noxafil
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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