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Product name : Isradipine
Item : cc164
Price : 1g, $650;2g, $1050; 5g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 75695-93-1
Molecular Weight : 371.39
Formula : C₁₉H₂₁N₃O₅
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Isradipine (Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM.It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack the interactive effects of isradipine and blockers or enhancers of nonselective cation channels (NSCCs) and Na+/Ca2+ exchangers (NCXs). Normal human gingival fibroblast Gin-1 cells were used. The [Ca2+]i was measured with the Ca2+-sensitive fluorescent dye fura-2/AM. Changes in the fluorescence intensity of fura-2 in the cells were recorded with a video-imaging analysis system. Ca2+ antagonists (nifedipine, verapamil, and diltiazem in the concentration range of 1 to 20 μM) other than isradipine also raised the [Ca2+]i.  [1][2]
 
Reference:
[1] Eur. J Med. Res. 2006, 11, 93-96.
[2] Int. J Neuropsychopharmacol. 2005, 8, 203-213.
 
 
Chemical Information
Molecular Weight (WM):
371.39
Formula:
C19H21N3O5
CAS No:
75695-93-1
Purity:
≥ 98%
Synonyms:
DynaCirc, Prescal, PN-200-110, Clivoten, Esradin
 
DMSO ≥ 74 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 74 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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