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Product name : BIX 01294
Item : cc235
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS :  935693-62-2
Molecular Weight : 490.64
Formula : C₂₈H₃₈N₆O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
BIX-01294, a diazepin-quinazolinamine derivative, is a histone-lysine methyltransferase (HMTase) inhibitor that modulates the epigenetic status of chromatin. BIX-01294 inhibits the G9aHMTase dependent levels of histone-3 lysine (9) methylation (H3K9me). Bix-01294 and valproic acid, a histone deacetylase (HDAC) inhibitor, may replace the requirement for ectopic OCT4 (POU5F1) and cMyc respectively in pluripotent stem cell induction (iPS) recipes.  [1][2]
 
Reference:
[1] Mol. Cell 2007, 25, 473-481.
[2] Nat. Struct. Mol. Biol. 2009, 16, 312-317.
 
 
Chemical Information
Molecular Weight (WM):
600.023
Formula:
C28H41Cl3N6O2
CAS No:
935693-62-2
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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