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Products > Receptor Tyrosine Kinase > ALK > RepSox (Synonyms: E-616452; SJN 2511)
Product name : RepSox (Synonyms: E-616452; SJN 2511)
Item : cc232
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 446859-33-2
Molecular Weight : 287.32
Formula : C₁₇H₁₃N₅
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
ALK5 inhibitor is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively). It is selective for ALK5 over a range of kinases, including p38 MAPK, JNK1 and GSK3 (IC50 > 16 μM). It enhances the efficiency of cellular reprogramming. [1][2]
 
Reference:
[1] J Med. Chem. 2004, 47, 4494-4506.
[2] Cell Stem Cell 2009, 9, 16-19.
 
 
Chemical Information
Molecular Weight (WM):
287.32
Formula:
C17H13N5
CAS No:
446859-33-2
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃       Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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