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Product name : PF 429242
Item : cc143
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 947303-87-9
Molecular Weight : 409.5643
Formula : C25H35N3O2
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
PF-429242 is a cell permeable, reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). PF429242 is selective for site 1 protease against a panel of serine proteases. PF 429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM). [1][2]
 
Reference:
[1] Bioorg. Med. Chem. Lett. 2007, 17, 4411-4414.
[2] J Pharmacol. Exp. Ther. 2008, 326, 801-808.
 
 
Chemical Information
Molecular Weight (WM):
482.49
Formula:
C25H37Cl2N3O2
CAS No:
947303-87-9
Purity:
≥ 98%
Synonyms:
PF 429242
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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