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Product name : AS 252424
Item : cc208
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 900515-16-4
Molecular Weight : 305.28
Formula : C₁₄H₈FNO₄S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
AS-252424 is a potent inhibitor of PI3K with selectivity for the γ isoform. AS252424 inhibits human recombinant PI3Kγ, α, β, and δ with IC50 values of 30, 940, 20,000, and 20,000 nM respectively. Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of Pl at the 3 position to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. [1][2]
 
Reference:
[1] Nat. Rev. Drug Discov. 2005, 4, 988-1004.
[2] J Med. Chem. 2006, 49, 3857-3871.
 
 
Chemical Information
Molecular Weight (WM):
305.28
Formula:
C14H8FNO4S
CAS No:
900515-16-4
Purity:
≥ 98%
Synonyms:
AS 252424
 
DMSO ≥ 61 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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