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Product name : Dalcetrapib (JTT 705)
Item : cc294
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 211513-37-0
Molecular Weight : 389.59
Formula : C₂₃H₃₅NO₂S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM. Dalcetrapib induces a conformational change in CETP, when added to human plasma. CETP-induced pre-β-HDL formation in human plasma is unchanged by Dalcetrapib ≤3 µM and increased at 10 µM. Dalcetrapib statistically and significantly increases pre-β-HDL formation.  [1][2]
 
Reference:
[1] J Med. Chem. 2000, 43, 3566-3572.
[2] Br. J Clin. Pharmacol. 2010, 70, 825-833.
 
 
Chemical Information
Molecular Weight (WM):
389.60
Formula:
C23H35NO2S
CAS No:
211513-37-0
Purity:
≥ 98%
Synonyms:
JTT705, JTT 705
 
DMSO ≥ 78 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 78 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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