Product name : PAC-1
Item : cc276
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 315183-21-2
Molecular Weight : 392.49
Formula : C₂₃H₂₈N₄O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM. Elevated caspase 3 level in cancer cell lines allows PAC1 to selectively induce apoptosis in a manner proportional to procaspase-3 concentration with IC50 of 0.35 μM for NCI-H226 cells to ~3.5 μM for UACC-62 cells. [1][2]
Reference:
[1] Nat. Chem. Biol. 2006, 2, 543-550.
[2] J Mol. Biol. 2009, 388, 144-158.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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