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Product name : SB 431542
Item : cc103
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 301836-41-9
Molecular Weight : 384.39
Formula : C₂₂H₁₆N₄O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
SB-431542 is a potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB 431542 stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells.  [1][2]
 
Reference:
[1] J Med. Chem. 2002, 45, 999-1001.
[2] Mol. Pharmacol. 2002, 62, 65-74.
 
 
Chemical Information
Molecular Weight (WM):
384.39
Formula:
C22H16N4O
CAS No:
301836-41-9, 1049727-65-2 (H2O)
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 77 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 45 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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