Apoptosis
Btk
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Product name : SB 431542
Item : cc103
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 301836-41-9
Molecular Weight : 384.39
Formula : C₂₂H₁₆N₄O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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SB-431542 is a potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB 431542 stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells. [1][2]
Reference:
[1] J Med. Chem. 2002, 45, 999-1001.
[2] Mol. Pharmacol. 2002, 62, 65-74.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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