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Products > Cell Metabolism > Factor Xa > Rivaroxaban (Xarelto)
Product name : Rivaroxaban (Xarelto)
Item : cc309
Price : 5g, $650;10g, $1050; 20g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 366789-02-8
Molecular Weight : 435.88
Formula : C₁₉H₁₈ClN₃O₅S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Rivaroxaban (Xarelto, BAY 59-7939) is an oral, direct inhibitor of Factor Xa with a Ki of 0.4 nM and IC50 of 0.7 nM for purified human FXa.Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. Rivaroxaban does not inhibit thrombin (activated Factor II), and no effects on platelets have been demonstrated.  [1][2]
 
Reference:
[1] J Thromb. Haemost. 2005, 3, 514-521.
[2] Diabetes 2009, 58, 641-651.
 
 
Chemical Information
Molecular Weight (WM):
435.88
Formula:
C19H18ClN3O5S
CAS No:
366789-02-8, 931385-22-7 (XHCl)
Purity:
≥ 98%
Synonyms:
BAY59-7939
 
DMSO ≥ 87 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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