Apoptosis
MAO
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Product name : Aprepitant (MK 0869)
Item : cc310
Price : 1g, $650;2g, $1050; 5g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 170729-80-3
Molecular Weight : 534.43
Formula : C₂₃H₂₁F₇N₄O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Aprepitant (MK-0869) is classified as an NK1 antagonist. Aprepitant (MK0869) has been shown to inhibit both the acute and delayed emesis induced by cytotoxic chemotherapeutic drugs by blocking substance P landing on receptors in the brains neurons. It has also been shown to increase the activity of the 5-HT3 receptor antagonists ondansetron and the corticosteroid dexamethasone, which are also used to prevent nausea and vomiting caused by chemotherapy. [1][2]
Reference:
[1] J Med. Chem. 1998, 41, 4607-4614.
[2] J Am. Chem. Soc. 2003, 125, 2129-2135.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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