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Product name : Nebivolol (R 67145)
Item : cc564
Price : 1g, $650;2g, $1050; 5g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 152520-56-4
Molecular Weight : 441.9
Formula : C₂₂H₂₆ClF₂NO₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Nebivolol has selective β1 receptor blocking activity with an IC50 value of 0.8 nM in a rabbit lung β1-adrenoceptor binding assay. Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and, in Europe, also for left ventricular failure. It is highly cardioselective under certain circumstances. [1][2]
 
Reference:
[1] Mol. Pharmacol. 1988, 34, 843-851.
[2] Br. J Pharmacol. 2001, 133, 1330-1338.
 
 
Chemical Information
Molecular Weight (WM):
441.90
Formula:
C22H25F2NO4.HCl
CAS No:
152520-56-4, 118457-14-0 (free base)
Purity:
≥ 98%
Synonyms:
R-67145, R67145
 
DMSO ≥ 88 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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