Apoptosis
MNK
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Product name : CI 1040 (PD 184352)
Item : cc-384
Price : 200mg, $650;500mg, $950; 1g $1650; 2g, $2850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 212631-79-3
Molecular Weight : 478.66
Formula : C₁₇H₁₄ClF₂IN₂O₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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PD184352 (CI-1040) is a highly selective non-competitive inhibitor of MEK (MKK1; MAPK kinase) and the closely related MKK2 with a Ki of 300 nM in vitro. It has anti-cancer activity, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell lines. [1][2]
Reference:
[1] Nature. Medicine 1999, 5, 810-816.
[2] Nature. 2006, 439, 358-362.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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