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Products > Neuro Signaling > AchR > Solifenacin (YM 905)
Product name : Solifenacin (YM 905)
Item : cc409
Price : 10mg, $95, 50mg, $295; 100mg, $545; 200mg, $995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Solifenacin (YM905) is a competitive muscarinic acetylcholine receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle. By preventing the binding of acetylcholine to these receptors, solifenacin reduces smooth muscle tone in the bladder, allowing the bladder to retain larger volumes of urine and reducing the number of micturition, urgency and incontinence episodes. Because of a long elimination half life, a once-a-day dose can offer 24 hour control of the urinary bladder smooth muscle tone. [1][2]
 
Reference:
[1] J Clin. Pharmacol. 2004, 44, 1023-1033.
[2] Drugs Today 2004, 40, 343-353.
 
 
Chemical Information
Molecular Weight (WM):
480.55
Formula:
C27H32N2O6
CAS No:
242478-38-2
Purity:
≥ 98%
Synonyms:
YM-905, Vesicare
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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