Apoptosis
MNK
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Product name : PD 98059
Item : cc-461
Price : 200mg, $650;500mg, $950; 1g $1650; 2g, $2850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 167869-21-8
Molecular Weight : 267.28
Formula : C₁₆H₁₃NO₃
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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PD 98059 is a potent, selective and cell-permeable inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase). It inhibits phosphorylation of MAP kinase by MAP kinase kinase. PD 98059 does not inhibit MAP kinase itself. IC50 values for PD 98059-induced effects are in the 1-20 µM range for many assays; it is somewhat weaker in inhibiting cell growth in monolayers or agar for some cell lines. [1][2]
Reference:
[1] Proc. Natl. Acad. Sci. USA, 1995, 92, 7686-7689.
[2] J Biol. Chem. 1995, 270, 13585-13588.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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