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Product name : PD 98059
Item : cc-461
Price : 10mg, $55; 50mg, $240; 100mg, $395; 200mg, $595
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
PD 98059 is a potent, selective and cell-permeable inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase). It inhibits phosphorylation of MAP kinase by MAP kinase kinase.  PD 98059 does not inhibit MAP kinase itself.  IC50 values for PD 98059-induced effects are in the 1-20 µM range for many assays; it is somewhat weaker in inhibiting cell growth in monolayers or agar for some cell lines.  [1][2]
 
Reference:
[1] Proc. Natl. Acad. Sci. USA, 1995, 92, 7686-7689.
[2] J Biol. Chem. 1995, 270, 13585-13588.
                                         
Chemical Information
Molecular Weight (WM):
267.28
Formula:
C16H13NO3
CAS No:
167869-21-8
Purity:
≥ 98%
Synonyms:
PD-98059, PD98059
 
DMSO ≥ 32g/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol ≥ 3 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
6months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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