Favorite  |  Set Home
Products > Cell Cycle > CDK > SNS 032 (BMS 387032)
Product name : SNS 032 (BMS 387032)
Item : cc229
Price : 10mg, $125; 50mg, $475; 100mg, $795; 200mg, $1095
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
SNS-032 (BMS387032) is a novel, potent and selective CDK inhibitor of CDK2, CDK7 and CDK9 with IC50 of 38 nM, 62 nM and 4 nM, respectively. CDK inhibitor SNS032 (BMS-387032)selectively binds to CDKs 2, 7, and 9, preventing their phosphorylation and activation; inhibition of CDK activity may result in cell cycle arrest, the induction of apoptosis and decreased tumor cell proliferation in susceptible tumor cell populations. This agent has been shown to sensitize radioresistant tumor cells to ionizing radiation.  [1][2]
 
Reference:
[1] Blood 2009, 113, 4637-4645.
[2] Neoplasia 2007, 9, 370-381.
 
 
Chemical Information
Molecular Weight (WM):
380.53
Formula:
C17H24N4O2S2
CAS No:
345627-80-7, 345627-90-9 (HCl)
Purity:
≥ 98%
Synonyms:
SNS 032, BMS 387032
 
DMSO ≥ 76 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 76 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
LY-2835219
LY-2835219
Price: 100mg, $495; 500mg, $1495;
R 547
R 547
Price: 5mg, $495; 10mg, $795; 50mg, $1795;
Kenpaullone
Kenpaullone
Price: 10mg, $75, 50mg, $345; 100mg, $595; 200mg, $995
Lee011
Lee011
Price: 100mg, $945; 200mg, $1485
PHA 848125
PHA 848125
Price: 10mg, $295; 50mg, $895; 100mg, $1295; 200mg, $2195
JNJ 7706621
JNJ 7706621
Price: 10mg, $325; 50mg, $775; 100mg, $1295; 200mg,$1675
Dinaciclib (SCH 727965)
Dinaciclib (SCH 727965)
Price: 10mg, $275; 50mg, $895; 100mg, $1345; 200mg, $2195
AT 7519
AT 7519
Price: 10mg, $195; 50mg, $595; 100mg, $995; 200mg, $1695