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Product name : PHA 793887
Item : cc404
Price : 10mg, $225; 50mg, $695; 100mg, $895; 200mg, $1475
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM, respectively. PHA793887 was also effective in vivo in both subcutaneous xenograft and primary leukemic disseminated models that better mimic naturally occurring human disease. [1][2]
 
Reference:
[1] Bioorg. Med. Chem. 2010, 18, 1844-1853.
[2] Exp. Hematol. 2010, 38, 259-269.
 
 
Chemical Information
Molecular Weight (WM):
361.48
Formula:
C19H31N5O2
CAS No:
718630-59-2, 718630-60-5 (HCl)
Purity:
≥ 98%
Synonyms:
PHA 793887
 
DMSO ≥ 72 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 72 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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