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Product name : Pimobendan
Item : cc586
Price : 2g, $650;5g, $1050; 10g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 74150-27-9
Molecular Weight : 334.37
Formula : C₁₉H₁₈N₄O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Pimobendan (Vetmedin) is a selective inhibitor of phosphodiesterase III (PDE III) with an IC50 value of 0.32 μM. Pimobendan is a positive inotrope. It sensitizes and increases the binding efficiency of cardiac myofibril to the calcium ions that are already present without increasing the consumption of oxygen and energy. Pimobendan also causes peripheral vasodilation by inhibiting the function of phosphodiesterase III. This results in decreased pressure, translating into smaller cardiac preload and afterload (decreases the failing heart's workload). [1][2]
 
Reference:
[1] J Cardiovasc. Pharmacol. 1991, 18, 17-27.
[2] Br. J Pharmacol. 1997, 121, 1549-1556.
 
 
Chemical Information
Molecular Weight (WM):
334.37
Formula:
C19H18N4O2
CAS No:
74150-27-9, 77469-98-8 (HCl)
Purity:
≥ 98%
Synonyms:
Acardi, Pimobendane
 
DMSO ≥ 67 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 5 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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