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Product name : PF 2545920
Item : cc134
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 898562-94-2
Molecular Weight : 392.45
Formula : C₂₅H₂₀N₄O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
PF-2545920 is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. The PDE10A enzyme is expressed primarily in the brain, mostly in the striatum, nucleus accumbens and olfactory tubercle, and is thought to be particularly important in regulating the activity of dopamine-sensitive medium spiny neurons in the striatum which are known to be targets of conventional antipsychotic drugs. [1][2]
 
Reference:
[1] J Pharmacol. Exp. Ther. 2009, 331, 574-590.
[2] J Med. Chem. 2009, 52, 5188-5196.
 
 
Chemical Information
Molecular Weight (WM):
392.45
Formula:
C25H20N4O
CAS No:
1292799-56-4
Purity:
≥ 98%
Synonyms:
PF2545920
 
DMSO ≥ 79 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 79 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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