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Product name : Avasimibe (CI 1011)
Item : cc104
Price : 10mg, $45; 50mg, $195; 100mg, $295; 200mg, $595
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Avasimibe (CI-1011) inhibits ACAT and P450 isoenzymes CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively. Avasimibe (CI1011) inhibits ACAT-1 expression and cholesterol ester synthesis in glioma cell lines. Avasimibe (CI 1011) inhibits the growth of the glioma cells by inducing cell cycle arrest and apoptosis due to caspase-8 and caspase-3 activation.   [1][2]
 
Reference:
[1] Circulation 2001, 103, 1778-1786.
[2] Atherosclerosis 1998, 136, 79-87.
 
 
Chemical Information
Molecular Weight (WM):
501.72
Formula:
C29H43NO4S
CAS No:
166518-60-1
Purity:
≥ 98%
Synonyms:
CI1011
 
DMSO ≥ 100 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 8 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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